David G. Affleck, MD's Professional Resume

BIBLIOGRAPHY

Original Publications

1. Gard, D.L., Affleck, D.G., Error, B.M.: Microtubule Organization, Acetylation, and Nucleation in Xenopus Laevis Oocytes: II. A Developmental Transition in Microtubule Organization during Early Diplotene. Dev Biol. 1995 Mar; 168(1):189-201.
2. Sullivan, D.J., Shelby, J., Shao, Y., Affleck, D.G., Hinson, D.M., Barton, R.G.: Melatonin and a 21-Adminosteroid Attenuate Shock After Hemorrhage, but Differentially Affect Serum Cytokines. J Surg Res. 1996 Jul 15; 64(1):13-8.
3. Affleck, D.G., Handrahan, D., Egger, M., Price, R.R.: The Laparoscopic Management of Appendicitis and Cholelithiasis During Pregnancy. Am J Surg. 1999 Dec;178(6):532-9.
4. Bull, D.A., Neumayer, L., Stringham, J.C., Meldrum, P., Affleck, D.G., Karwande, S.V.: CABG with Cardiopulmonary Bypass vs. OPCAB: Does Eliminating the Pump Reduce Morbidity and Cost? Ann Thorac Surg. 2001 Jan;71(1):170-3; discussion 173-5.
5. Affleck, D.G., Yu, L., Bull, D.A., Kim, S.Y.: Augmentation of Myocardial Transfection using TerplexDNA: A Novel Gene Delivery System. Gene Therapy. 2001 Feb;(8):349-353
6. Affleck, D.G., Edelman, L., Morris, S.E., Saffle, J.R.: Assessment of Tissue Viability in Complex Extremity Injuries: Utility of the Pyrophosphate Nuclear Scan. J Trauma. 2001 Feb;50(20):263-9.
7. Affleck, D.G., Bull, D.A., Stringham, J.C., Haller J.R., Davis, R.K., Karwande, S.V.: Functional Outcome and Survival Following Pharyngolaryngoesophagectomy for Cancer. Am J Surg. 2000 Dec;180(6):546-50.
8. Affleck, D.G., Bull, D.A., Bailey, S.H., Albanil, A., Connors, R., Stringham, J.C., Karwande, S.V.: PDGFBB Increases Myocardial Production of VEGF: Shift in VEGF mRNA Splice Variants after Direct Injection of bFGF, PDGFBB and PDGFAB. J Surg Res. 2002 Oct;107(2).
9. Affleck, D.G., Bull, D.A., Albanil, A., Shao, Y., Brady, J., Karwande, S.V., Eichwald, E.J., Shelby, J.: IL-18 Production Following Murine Cardiac Transplantation: Correlation with Histologic Rejection and the Induction of Interferon. J Interferon Cytokine Res. 2001 Jan;21(1):1-9.
10. Affleck, D.G., Bull, D.A., Bailey, S.H., Albanil, A., Connors, R., Stringham, J.C., Karwande, S.V.: PDGFBB Induces Myocardial Production of VEGF: Shift in VEGF mRNA Isoforms after Treatment with Recombinant Angiogenic Compounds. J Surg Res 100, 233-244 (2001).
11. Affleck, D.G., Moazami, N., Hess, R.L., Moon, M.R., Pasque, M.K., Lawton, J.S., Guleserian, K., Bailey, M.S., Damiano, R.J.: Morbidity and Mortality of Cardiac Surgery Following Renal Transplantation. Am J Transplantation 2003 May:5(3)526.
12. DeWitt, C.J., Affleck, D.G., Jacobsohn, E., Avidan, M.S., Tymkew, H., Hill, L.L., Zanaboni, P.B., Moazami, N., Smith, J.R.: Inhaled Prostacyclin is Safe, Effective and Affordable in Patients with Pulmonary Hypertension, Right Heart Dysfunction and Refractory Hypoxemia after Cardiothoracic Surgery. J Thorac Cardiovasc Surg 2004;127(40):1058-67.
13. Bailey, S.H., Bull, D.A., Zebrack, J.B., Litwin, S.H., Affleck, D.G., Kim, S.W.: Terplex DNA Mediated VEGF-165 Gene and Protein Therapy Augments Recovery of Left Ventricular Function Following Acute Myocardial Ischemia. Circulation 2001;104(17) II-149.
14. Affleck, D.G., Moon, M.: Evolution in Treatment of Annuloaortic Ectasia for Marfan Syndrome: Valve-sparing Techniques Correct Aortic Insufficiency. CHEST 2003;124(4):266S.
15. Affleck, D.G., Barner, H.B., Bailey, M.D., Maniar, H., Prasad, S.M., Damiano, R.J. Jr.: Flow Dynamics of the Internal Thoracic and Radial Artery "T-Graft." Ann Thor Surg 2004;78(4)1290-94.

Abstracts Accepted

1. Sullivan, D.J., Shelby, J., Shao, Y., Affleck, D.G., Hinson, D.M., Barton, R.G.: Melatonin and a 21-Aminosteroid Attenuate Shock after Hemorrhage, but Differentially Affect Serum Cytokines. Association for Academic Surgery, Dearborn, Michigan. November 9-11, 1995.
2. Sullivan, D.J., Affleck, D.G., Van Boerum, D.H., Mone, M.C., Hinson, D.M., Barton, R.G.: Adult Respiratory Distress Syndrome (ARDS) Mortality is Related to the Presence of Multiple Organ Failure and to Ventilator Pressures in Surgical Patients. Southwest Surgical Congress, October 24, 1995.
3. Affleck, D.G., Handrahan, D., Egger, M., Price, R.R.: The Laparoscopic Management of Appendicitis and Cholelithiasis During Pregnancy. 51st Annual Meeting – Southwestern Surgical Congress. Coronado, CA. April 19-21 1999, pp.59.
4. Affleck, D.G., Bull, D.A., Stringham, J.D., Haller, J.R., Davis, R.K., Karwande, S.V.: Pharyngolaryngoesophagectomy: Functional Outcome and Survival Following Surgical Management of Neoplasms of the Larynx, Hypopharynx and Cervical Esophagus. 52nd Annual Meeting of the Southwest Surgical Congress, Colorado Springs, Colorado. April 9-12, 2000 pp.51.
5. Affleck, D.G., Edelman, L., Morris, S.E., Saffle, J.R. Assessment of Tissue Viability in Complex Extremity Injuries: Utility of the Pyrophosphate Nuclear Scan. 30th Annual Meeting of the West Trauma Association, Lake Tahoe, California. February 28, 2000.
6. Affleck, D.G., Bailey, S.H., Bull, D.A., Connors, R., Haller, J.R., Karwande, S.V., David, R.K. Pharyngolaryngoesophagectomy for Hypopharyngeal Cancer. The American Broncho-Esophagological Association, May 2001.
7. Bailey, S.H., Affleck, D.G., Bull, D.A., Stringham, J.C., Karwande, S.V. Is the Transhiatal or Transthoracic Esophagectomy Superior for Malignancy? 53rd Annual Meeting of the Southwestern Surgical Congress, Cancun, Mexico. April 2001.
8. Yu, L., Affleck, D.G., Bailey, S.H., Bull, D.A., Kim, S.W. Augmented Myocardial Transfection Using a Novel Non-Viral Delivery System: TerplexDNA. American Heart Association Scientific Conference on Therapeutic Angiogenesis and Myocardial Laser Revisualization, Santa Fe, New Mexico. January 24-27, 2001.
9. Affleck, D.G., Moazami, N., Hess, R.L., Moon, M.R., Pasque, M.K., Lawton, J.S., Guleserian, K., Bailey, M.S., Damiano, R.J. Morbidity and Mortality of Cardiac Surgery Following Renal Transplantation. American Society Transplant Surgeons, Washington, DC, May 30-June 4, 2003.
10. Affleck, D.G., Jacobsohn, J., Hill, L., Dewitt, C., Avidan, M., Hahn, H., Moon, M., Damiano, R., Moazami, N.: Inhaled Prostacyclin is a Safe and Effective Alternative to Nitric Oxide for the Treatment of Right Heart Failure and Pulmonary Hypertension after Cardiac Surgery. Western Thoracic Association June 2003.
11. Affleck, D.G., Barner, H.B., Bailey, M.S., Maniar, H., Prasad, S.M., Damiano, R.J., Jr.: Flow Dynamics of the Internal Thoracic and Radial Artery "T-Graft." Southern Thoracic Surgical Association, Bonita Springs, Florida November 2003. pp60.
12. Affleck, D.G., Moon, M.: Evolution in Treatment of Annuloaortic Ectasia for Marfan Syndrome: Valve-Sparing Techniques Correct Aortic Insufficiency. CHEST, American College of Chest Physicians, Orlando, Florida, October 2003.
13. Affleck, D.G., Moon, M.: Valve-Sparing Aortic Root Replacement for Marfan Syndrome. Video Abstract Southern Thoracic Surgical Association, Bonita Springs, Florida, November 2003. pp17.
14. Affleck, D.G., Schorlemmer, G., Phillips, A., Sharp, S., Thorne, J.K.: Minimally Invasive Maze is Safe, Reproducible and Effective For the Treatment of Paroxysmal and Persistent Atrial Fibrillation. Submitted 32nd Annual Meeting Western Thoracic Surgical Asociation. Sun Valley, ID. June 21-24, 2006.

Oral Presentations

1. Affleck, D.G., Laparoscopic Cholecystectomy During Pregnancy-LDS Hospital Experience 1998-1998
   Resident Research Forum
   Snowbird, UT. February 1998.
2. Affleck, D.G., The Laparoscopic Management of Appendicitis and Cholelithiasis During Pregnancy.
   Southwestern Surgical Congress, 51st Annual Meeting
   Coronado, CA. April 19-21, 1999.
3. Affleck, D.G., The Laparoscopic Management of Appendicitis and Cholelithiasis During Pregnancy.
   Wisconsin Surgical Club
   Salt Lake City, UT. April 28, 1999.
4. Affleck, D.G., Assessment of Tissue Viability in Complex Extremity Injuries: Utility of the Pyrophosphate Nuclear Scan.
   Western Trauma, 30th Annual Meeting
   Lake Tahoe, CA. February 28, 2000.
5. Affleck, D.G., Augmentation of Myocardial Transfection Using TerplexDNA
   Bayer Research Forum
   Snowbird, UT. March 31, 2000.
6. Affleck, D.G., Gene Therapy and the Cardiovascular System: From Benchtop to Clinic, Tissue Engineering of the Myocardium
   University of Utah Grand Rounds
   Salt Lake City, UT. November 8, 2000.
7. Affleck, D.G., PDGFBB Increases Myocardial Production of VEGF: Shift in VEGF mRNA Splice Variants after Direct Injection of bFGF, PDGFBB and PDGFAB.
   Eccles Institute of Human Genetics Research Forum
   Salt Lake City, UT. March 23, 2001.
8. Affleck, D.G., Pharyngolarnygoesophagectomy in Hypopharyngeal Cancer.
   American Broncho-Esophagological Association
   Palm Deseret, CA. May 14-15, 2001.
9. Affleck, D.G., PDGFBB Increases Myocardial Production of VEGF: Shift in VEGF mRNA Splice Variants after Direct Injection of bFGF, PDGFBB and PDGFAB.
   Association for Academic Surgery
   Milwaukee, WI. November 19, 2001.
10. Affleck, D.G., Radical Resection for T4 Lung Cancer: Results of Treatment and Lessons Learned
    Washington University Cardiothoracic Surgery Grand Rounds
    St. Louis, MO. December 16, 2002
11. Affleck, D.G., OPCAB: The Future of Cardiac Surgery.
    Washington University Cardiothoracic Surgery Grand Rounds
    St. Louis, MO. February 24, 2003
12. Affleck, D.G., Patient Prosthetic Mismatch: Why not Place a 19mm St. Jude Valve in Very Patient? Evaluation of BSA and Ventricular Mass Regression
    Washington University Cardiothoracic Surgery Grand Rounds
    St. Louis, MO. April 21, 2003
13. Affleck, D.G., Moon, M.: Evolution in Treatment of Annuloaortic Ectasia for Marfan Syndrome.
    CHEST, American College of Chest Physicians
    Orlando, Florida. October 2003
14. Affleck, D.G., TACR: Total Arterial Coronary Revascularization. Arteries, Veins and Why We Do What We Do. Or Should We?
    Washington University Cardiothoracic Surgery Grand Rounds
    St. Louis, MO. October 13, 2003.
15. Affleck, D.G., Flow Dynamics of the Internal Thoracic and Radial Artery "T-Graft."
    Southern Thoracic Surgical Association
    Bonita Springs, Florida. November 2003.
16. Affleck, D.G., Valve-Sparing Aortic Root Replacement for Marfan Syndrome.
    Southern Thoracic Surgical Association
    Bonita Springs, Florida. November 2003
17. Affleck, D.G., Novel Approach to Failed Aortic Valve Conduit Replacement
    St. Louis Surgical Society
    University Club, St. Louis, MO. December 2003
18. Affleck, D.G., Cardiovascular Disease and Cardiac Surgery in 2005
    Public Lecture Forum
    St. Mark's Hospital, Salt Lake City, UT. July 21, 2005
19. Affleck, D.G., Atrial Fibrillation: Surgical Considerations
    Medical Grand Rounds
    St. Mark's Hospital, Salt Lake City, UT. August 2, 2005

Book Chapters

1. Bull, D.A., Bailey, S.H., Yu, L., Affleck, D.G., Kim, S.W.: Development and Application of Polymeric Gene Carriers for Cardiovascular Disease. In: Pharmaceutical Perspectives on Nucleic Acid Based Therapeutics. Gordon and Breach Publishing, June 2001.

Posters/Misc.

1. Yu, L., Affleck, D.G., Bailey, S.H., Bull, D.A., Kim, S.W.: Augmented Myocardial Transfection using a Novel Non-Viral Delivery System: TerplexDNA. American Heart Association Scientific Conference on Therapeutic Angiogenesis and Myocardial Laser Revascularization, Santa Fe, New Mexico. January 24-27, 2001.
2. Bailey, S.H., Affleck, D.G., Bull, D.A., Stringham, J.C., Karwande, S.V.: Is the Transhiatal or Transthoracic Esophagectomy Superior for Malignancy? 53rd Annual Meeting of the Southwestern Surgical Congress, Cancun, Mexico. April 2001.
3. Affleck, D.G., Moazami, N., Hess, R.L., Moon, M.R., Pasque, M.K., Lawton, J.S., Guleserian, K., Bailey, M.S., Damiano, R.J.: Renal Allografting Alters Outcome after Major Cardiac Surgery: Graft Function, Morbidity, and Effect on Operative and Long Term Survival. American Transplant Congress, Washington, D.C., May 30-June 4, 2003.
4. Affleck, D.G., Moon, M.: Valve-Sparing Aortic Root Replacement for Marfan Syndrome. Video Abstract. CTSNET On-Line Video Publication, July 2004.
5. Affleck, D.G., Moon, M.: Valve-Sparing Aortic Root Replacement for Marfan Syndrome. Division of Cardiothoracic Surgery, Washington University School of Medicine. 52nd Annual Meeting of STSA. Website Video Publication.